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Article

Molecular profiles of hereditary epithelial ovarian cancers and their implications for the biology of this disease.

Molecular oncology - 1 Apr 2009

Jazaeri Amir A

Abstract excerpt

BRCA1 and BRCA2 germline mutations account for the majority of hereditary ovarian cancers and comprise 10% of total cases. Ovarian cancers arising from these mutations exhibit both overlapping and distinct clinical and molecular features. The expression profiles of sporadic ovarian cancers show similarities to those of BRCA1 and BRCA2-related tumors suggesting that BRCA-related pathways may be involved in their...

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Identifiers

PMID: 19383376
DOI: 10.1016/j.molonc.2009.01.001
PMCID: PMC5527878

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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