Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive analysis of 989 patients with breast or ovarian cancer provides BRCA1 and BRCA2 mutation profiles and frequencies for the German population.

International journal of cancer - 1 Feb 2002

Meindl A

Abstract excerpt

The main focus of this German-wide multi-center study was to establish a BRCA1/2 mutation profile and to determine family types with high frequencies of mutations in these genes. In a comprehensive study, the entire coding sequences of the breast cancer genes BRCA1 and BRCA2 were analyzed in 989 unrelated patients from German breast/ovarian cancer families. A total of 77 BRCA1 and 63 BRCA2 distinct deleterious...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Founder Effect
Share to Frameshift Mutation
Share to Genes, BRCA1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA2

Share to Germany

Share to Neoplasms, Multiple Primary

Share to Neoplastic Syndromes, Hereditary

Share to RNA Splicing

Source

Identifiers

PMID: 11802209
DOI: 10.1002/ijc.1626

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive analysis of 989 patients with breast or ovarian cancer provides BRCA1 and BRCA2 mutation profiles and frequencies for the German population.PMID 11802209Read ↗

BRCA1 and BRCA2 germline mutation analysis from a cohort of 1267 patients at high risk for breast cancer in Brazil.Semantic proximity Read ↗

BRCA1 and BRCA2 mutation prevalence and clinical characteristics of a population-based series of ovarian cancer cases from Denmark.Semantic proximity Read ↗

Prevalence of BRCA1/2 germline mutations in 21 401 families with breast and ovarian cancer.Semantic proximity Read ↗

BRCA1 and BRCA2 germline mutation spectrum and frequencies in Belgian breast/ovarian cancer familiesSemantic proximity Read ↗

The role of BRCA1/2 in hereditary and familial breast and ovarian cancersSemantic proximity Read ↗

BRCA1 and BRCA2: the genetic testing and the current management options for mutation carriers.Semantic proximity Read ↗

High prevalence of BRCA1 founder mutations in Greek breast/ovarian families.Semantic proximity Read ↗

Novel BRCA1 and BRCA2 germline mutations and assessment of mutation spectrum and prevalence in Italian breast and/or ovarian cancer families.Semantic proximity Read ↗

Novel and Recurrent BRCA1/BRCA2 Germline Mutations in Patients with Breast /Ovarian Cancer: A Series from the South of TunisiaSemantic proximity Read ↗

Novel germline mutations and unclassified variants of BRCA1 and BRCA2 genes in Chinese women with familial breast/ovarian cancer.Semantic proximity Read ↗

Next generation sequencing analysis of BRCA1 and BRCA2 identifies novel variations in breast cancer.Semantic proximity Read ↗

Prevalence of deleterious germline variants in risk genes including BRCA1/2 in consecutive ovarian cancer patients (AGO-TR-1).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.