Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

T follicular regulatory cells in mice and men.

Immunology - 1 Sept 2017

Maceiras Ana Raquel, Fonseca Valter R, Agua-Doce Ana, Graca Luis

Abstract excerpt

It has long been known that CD4 T cells are necessary to provide help to B cells, triggering a germinal centre (GC) reaction where affinity maturation and isotype switching occur. However, the nature of the dedicated CD4 helper T cells, known as T follicular helper (Tfh), was only recently described. Here, we review the biology and function of the recently described T follicular regulatory (Tfr) cells, another...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to Autoimmunity
Share to Cytokines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germinal Center

Share to Immune System Diseases

Share to T-Lymphocyte Subsets

Share to T-Lymphocytes, Regulatory

Share to Thymus Gland

Source

Open in PubMed Open full text

Identifiers

PMID: 28617936
DOI: 10.1111/imm.12774
PMCID: PMC5543727

Genes

CXCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

T follicular regulatory cells in mice and men.PMID 28617936Read ↗

Several Follicular Regulatory T Cell Subsets With Distinct Phenotype and Function Emerge During Germinal Center Reactions.Semantic proximity Read ↗

T‐follicular helper cell differentiation and the co‐option of this pathway by non‐helper cellsSemantic proximity Read ↗

A follicular regulatory Innate Lymphoid Cell population impairs interactions between germinal center Tfh and B cellsSemantic proximity Read ↗

Regulatory T-cells: diverse phenotypes integral to immune homeostasis and suppression.Semantic proximity Read ↗

Transcriptional and epigenetic regulation of follicular T-helper cells and their role in autoimmunitySemantic proximity Read ↗

CD4+CD8+ T follicular helper cells regulate humoral immunity in chronic inflammatory lesionsSemantic proximity Read ↗

Functional differentiation and regulation of follicular T helper cells in inflammation and autoimmunity.Semantic proximity Read ↗

Biology and clinical relevance of follicular cytotoxic T cellsSemantic proximity Read ↗

Spatial distribution and function of T follicular regulatory cells in human lymph nodes.Semantic proximity Read ↗

Molecular Control of Follicular Helper T cell Development and DifferentiationSemantic proximity Read ↗

CD8+ regulatory T cells-A distinct T-cell lineage or a transient T-cell phenotype?Semantic proximity Read ↗

Regulatory T cell function in autoimmune diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.