Article

Desiccation-induced DNA damage facilitates drug resistance in <i>Mycobacterium tuberculosis</i>

2025-06-04

Abstract excerpt

<h4>ABSTRACT</h4> Mycobacterium tuberculosis (Mtb) is an obligate human pathogen that depends on its ability to spread from host-to-host to survive as a species. Yet, knowledge of transmission-specific traits remains lacking. Here, we report the discovery of a specific adaptive response to desiccation, a stress intrinsically linked to the generation of the aerosol droplets within which Mtb transmits. We show that...

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Literature Corpus work: 03c0cf69-0350-5a31-8510-1842ed1be57b
DOI: 10.1101/2025.06.04.657859

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