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Potential of Acyclovir, Allopurinol and B Vitamins for the Treatment of Mpox Viral Infection; Insight from Molecular Docking of the Mpox Virus Multi-Domain DNA Polymerase

2025-04-08

Abstract excerpt

Unpredictable emerging and re-emerging of Mpox virus (MPXV) outbreaks account for urgent interventions. While no drug has been approved for Mpox treatment, repurposing of nucleoside analog drugs such as tecovirimat and cidofovir is the current focus of many intervention initiatives. Intrigued by their molecular structural similarities, we hypothesized that acyclovir, allopurinol, and B vitamins, which structurally...

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Literature Corpus work
03be8da7-a2ea-5f5e-8128-cadebd718f54
DOI
10.20944/preprints202504.0714.v1
Open publication

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Potential of Acyclovir, Allopurinol and B Vitamins for the Treatment of Mpox Viral Infection; Insight from Molecular Docking of the Mpox Virus Multi-Domain DNA PolymeraseDOI 10.20944/preprints202504.0714.v1
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