Article

Virus-host protein-protein interactions as molecular drug targets for arboviral infections

2022-08-04

Abstract excerpt

Arboviruses have the potential to spread quickly and cause a global health emergency. These are RNA viruses that use RNA-dependent RNA polymerase (RdRp) for their replication. RdRp lacks proofreading activity, leading to high error rates, low replicative fidelity, and more genetic variability. In addition, shorter generation time and faster evolutionary rate of these viruses lead to re-emergence and recurrence of...

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Literature Corpus work: 7fde03ef-2b59-58fa-a4f1-e8f6baf825e3
DOI: 10.3389/fviro.2022.959586

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