Article

Structure-Guided Repurposing of SARS-CoV-2 Compounds Identifies Putative Inhibitors of Mpox Viral Enzymes

2026-08-13

Abstract excerpt

<title>Abstract</title> <p>Mpox remains a therapeutically underserved orthopoxvirus infection, and clinical evidence reinforces the need for antivirals acting through mechanisms distinct from tecovirimat. This study investigated whether a SARS-CoV-2 antiviral chemical library could be repurposed against three structurally characterised Mpox targets: the core protease, VP39 mRNA cap methyltransferase and poxin nuc...

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Literature Corpus work: 16a5b689-4137-543e-8b14-32046ab28550
DOI: 10.21203/rs.3.rs-10617852/v1

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Structure-Guided Repurposing of SARS-CoV-2 Compounds Identifies Putative Inhibitors of Mpox Viral EnzymesDOI 10.21203/rs.3.rs-10617852/v1Read

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