Article

The Hunt for antipox compounds against Monkeypox Virus Thymidylate Kinase and scaffolding protein leveraging Pharmacophore modeling, molecular docking, ADMET Studies, and molecular dynamics simulation studies

2023-08-30

Abstract excerpt

<title>Abstract</title> <p>Cases of the monkeypox virus have been recorded in non-endemic nations and have continued to be reported in several endemic nations since early May 2022 [1]. In this study, we modeled MPXV Thymidylate Kinase (TMPK) and scaffolding protein (D13), and these models and their templates were taken for small molecule screening against 602,413 small molecules using pharmacophore modeling and m...

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Literature Corpus work: d46a4b51-5be6-5af6-b99b-cd90da3e07bb
DOI: 10.21203/rs.3.rs-3306551/v1

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