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Acute myeloid leukemia with inv(16)(p13.1q22) and deletion of the 5’MYH11/3’CBFB gene fusion: a report of two cases and literature review.

2020-01-17

Abstract excerpt

<title>Abstract</title> <p>Background Abnormalities of chromosome 16 are found in about 5-8% of acute myeloid leukemia (AML). The AML with inv(16)(p13.1q22) or t(16;16)(p13.1;q22) is associated with a high rate of complete remission (CR) and favorable overall survival (OS) when treated with high-dose Cytarabine. At the inversion breakpoints, deletion of 3’ CBFB has been reported, but most of them were studied by...

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Literature Corpus work
03b71974-c14c-5f25-a504-22b0a5546a3a
DOI
10.21203/rs.2.19366/v2
Open publication

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