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Article

Integrative immunophenotypic and genetic characterization of acute myeloid leukemia with CBFB rearrangement.

American journal of clinical pathology - 4 Nov 2024

Sameeta Fnu, Wang Sa A, Tang Zhenya, Khoury Joseph D, Fang Hong, Wang Dylan, Xu Jie, Li Shaoying, Hu Zhihong, Hu Shimin, Jorgensen Jeffrey L, Medeiros L Jeffrey, Wang Wei

Abstract excerpt

OBJECTIVES: We sought to characterize the immunophenotype of acute myeloid leukemia (AML) with CBFB rearrangement and correlate the results with cytogenetic and molecular data. METHODS: Sixty-one cases of AML with CBFB rearrangement were evaluated. RESULTS: The sample population consisted of 33 men and 28 women, with a median age of 49 years. Flow cytometry immunophenotypic analysis showed that myeloblasts were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38801226
DOI: 10.1093/ajcp/aqae060

Genes

CBFB
CD34
KIT
NRAS
CD38
CD7
FLT3
MYH11
NF1
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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