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Article

Genetic abnormalities in core binding factor acute myeloid leukemia.

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2017

Ishikawa Yuichi

Abstract excerpt

Acute myeloid leukemia (AML) is a genetically heterogeneous disease, and its prognosis is stratified on the basis of chromosomal and genetic alterations. Core binding factor (CBF) leukemia consists of AML with t (8;21) (p22;q22) and inv16 (q16q16) /t (16;16) (q16;q16) and is included in AML with recurrent genetic abnormality according to WHO classification. Although CBF-AML is categorized as favorable-risk AML,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28883285
DOI: 10.11406/rinketsu.58.991

Genes

CBFB
MYH11
RUNX1
ASXL2
CCND2
DHX15
FLT3
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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