Article

Podocyte lineage marker expression is preserved across Wilms tumor subtypes and enhanced in tumors harboring the SIX1/2 p.Q177R mutation

2022-11-02

Abstract excerpt

<h4>SUMMARY</h4> Wilms tumors present as an amalgam of varying proportions of three tissues normally located within the developing kidney, one being the multipotent nephron progenitor population. While incomplete differentiation of the nephron progenitors is widely-considered the underlying cause of tumor formation, where this barrier occurs along the differentiation trajectory and how this might promote therapeu...

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Literature Corpus work: 03878bea-a6b7-5804-8478-c4e60d28f037
DOI: 10.1101/2022.11.02.514796

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