Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Six2 Defines and Regulates a Multipotent Self-Renewing Nephron Progenitor Population throughout Mammalian Kidney Development

1 Aug 2008

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Kidney Cyst Diseases
Share to Renal and related cancers
Share to Renal cell carcinoma treatment

Source

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 18682239
DOI: 10.1016/j.stem.2008.05.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Six2 Defines and Regulates a Multipotent Self-Renewing Nephron Progenitor Population throughout Mammalian Kidney DevelopmentPMID 18682239Read ↗

Six2 and Wnt Regulate Self-Renewal and Commitment of Nephron Progenitors through Shared Gene Regulatory NetworksSemantic proximity Read ↗

Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulatorsSemantic proximity Read ↗

Eya1 Interacts with Six2 and Myc to Regulate Expansion of the Nephron Progenitor Pool during NephrogenesisSemantic proximity Read ↗

Fate-mapping within human kidney organoids reveals conserved mammalian nephron progenitor lineage relationshipsSemantic proximity Read ↗

Notch signaling promotes nephrogenesis by downregulating Six2Semantic proximity Read ↗

Six1 and Six4 are essential for Gdnf expression in the metanephric mesenchyme and ureteric bud formation, while Six1 deficiency alone causes mesonephric-tubule defectsSemantic proximity Read ↗

Haploinsufficiency for the Six2 gene increases nephron progenitor proliferation promoting branching and nephron number.Semantic proximity Read ↗

Renal progenitors: an evolutionary conserved strategy for kidney regenerationSemantic proximity Read ↗

Genetic determination of nephrogenesis: the Pax/Eya/Six gene networkSemantic proximity Read ↗

Identification and Characterization of the Wilms Tumor Cancer Stem CellSemantic proximity Read ↗

Kidney Nephron DeterminationSemantic proximity Read ↗

The FGF, TGFβ and WNT axis Modulate Self-renewal of Human SIX2+ Urine Derived Renal Progenitor CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.