Article

Benzofuran sulfonates and small self-lipid antigens activate type II NKT cells via CD1d

2021-03-06

Abstract excerpt

Natural Killer T (NKT) cells detect lipids presented by CD1d. Most studies focus on type I NKT cells that express semi-invariant αβ T cell receptors (TCR) and recognise α-galactosylceramides. However, CD1d also presents structurally distinct lipids to NKT cells expressing diverse TCRs (type II NKT cells) but our knowledge of the antigens for type II NKT cells is limited. An early study identified an NKT cell agoni...

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Literature Corpus work: 0374d31a-16b0-503d-88a1-15e57c1a24e2
DOI: 10.1101/2021.03.05.433980

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