Article

A conserved human population of TRAV26+ type II Natural Killer T cells solely recognise CD1d

2025-12-05

Abstract excerpt

<title>Abstract</title> <p> Most studies of CD1d-restricted Natural killer T cells (NKT) have focussed on type I <italic>TRAV10-TRAJ18</italic> <sup>+</sup> NKT cells that recognise the glycolipid a-GalCer. Our understanding of type II NKT cells, their TCR gene usage and ligand diversity remains unclear. Here, using CD1d tetramers carrying diverse endogenous lipids (CD1d-endo), we identified public human TRAV...

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Literature Corpus work: 7ed51cb7-cbc8-5108-a180-d529a0aeecb1
DOI: 10.21203/rs.3.rs-7004764/v1

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