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Article

Basophil and mast cell activation tests by flow cytometry in immediate drug hypersensitivity: Diagnosis and beyond.

Journal of immunological methods - 1 Aug 2021

Elst Jessy, Sabato Vito, van der Poorten Marie-Line M, Van Gasse Athina L, Van Houdt Michel, Bridts Chris H, Walschot Mark, Timmermans Jean-Pierre, Pintelon Isabel, Mertens Christel, Ebo Didier G

Abstract excerpt

Immediate drug hypersensitivity reactions (IDHRs) constitute a significant health issue with serious consequences of diagnostic error. The primary diagnostics to document IDHRs usually consists of quantification of drug-specific IgE (sIgE) antibodies and skin tests. Unfortunately, the positive predictive value (PPV) and negative predictive value (NPV) of these tests are not absolutely, which leaves room for new...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33933471
DOI: 10.1016/j.jim.2021.113050

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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