Article

Predicting drug sensitivity of cancer cells based on DNA methylation levels

2020-08-25

Abstract excerpt

Cancer cell lines, which are cell cultures developed from tumor samples, represent one of the least expensive and most studied preclinical models for drug development. Accurately predicting drug response for a given cell line based on molecular features may help to optimize drug-development pipelines and explain mechanisms behind treatment responses. In this study, we focus on DNA methylation profiles as one type...

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Literature Corpus work: 0342654e-3831-5e36-a1e8-b8019e5714a7
DOI: 10.1101/2020.08.25.266049

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