Article

Predicting Tumor Response to Drugs Based on Gene-expression Biomarkers of Sensitivity Learned From Cancer Cell Lines

2020-08-12

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: human cancer cell line profiling and drug sensitivity studies provide valuable information about the therapeutic potential of drugs and their possible mechanisms of action. The goal of those studies is to translate the findings from <italic>in vitro</italic> studies of cancer cell lines into <italic>in vivo</italic> therapeutic relevance and, eventually, patient...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7e4aa67b-5e8e-5608-9b94-9dca01731520
DOI: 10.21203/rs.3.rs-51060/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Predicting Tumor Response to Drugs Based on Gene-expression Biomarkers of Sensitivity Learned From Cancer Cell LinesDOI 10.21203/rs.3.rs-51060/v1Read

Predicting Tumor Response to Drugs based on Gene-Expression Biomarkers of Sensitivity Learned from Cancer Cell LinesSemantic proximity Read

Drug Sensitivity Prediction From Cell Line-Based Pharmacogenomics Data: Guidelines for Developing Machine Learning ModelsSemantic proximity Read

Dr.Paso: Drug response prediction and analysis system for oncology researchSemantic proximity Read

A Deep Learning Framework for Prediction of Clinical Drug Response of Cancer Patients and Identification of Drug Sensitivity Biomarkers using Preclinical SamplesSemantic proximity Read

Predicting drug response from single-cell expression profiles of tumoursSemantic proximity Read

Gene isoforms as expression-based biomarkers predictive of drug response <i>in vitro</i>Semantic proximity Read

BKDRP: A Biological Knowledge-Driven Approach for Drug Response Prediction Using Multi-Omics Data in Cancer Cell LinesSemantic proximity Read

Cancer drug sensitivity prediction from routine histology imagesSemantic proximity Read

Pan-Cancer Drug Sensitivity Prediction from Gene Expression using Deep LearningSemantic proximity Read

Interactive webtool for analyzing drug sensitivity and resistance associated with genetic signatures of cancer cell linesSemantic proximity Read

Predicting drug sensitivity of cancer cells based on DNA methylation levelsSemantic proximity Read

Gene expression based inference of drug resistance in cancerSemantic proximity Read