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Article

Rationalizing Drug Response in Cancer Cell Lines.

Journal of molecular biology - 14 Sept 2018

Juan-Blanco Teresa, Duran-Frigola Miquel, Aloy Patrick

Abstract excerpt

Cancer cell lines (CCLs) play an important role in the initial stages of drug discovery allowing, among others, for the screening of drug candidates. As CCL panels continue to grow in size and diversity, many polymorphisms in genes encoding drug-metabolizing enzymes, transporters and drug targets, as well as disease-related genes have been linked to altered drug sensitivity. However, identifying the correlation...

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Identifiers

PMID: 29626539
DOI: 10.1016/j.jmb.2018.03.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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