Article

The EGFR-HSF1 axis accelerates the tumorigenesis of pancreatic cancer

2020-12-31

Abstract excerpt

<h4>Background: </h4> Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant diseases because of its non-symptomatic tumorigenesis. We previous found heat shock factor 1 (HSF1) was critical for PDAC progression and the aim of this study was to clarified the mechanisms on early activation of HSF1 and its role in the pancreatic cancer tumorigenesis. <h4>Methods: </h4>: The expression and location of HS...

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Literature Corpus work: 03065b2e-19d7-5192-bea1-2c5cf2f67e8b
DOI: 10.21203/rs.3.rs-53955/v2

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