Article

Concomitant AD and DLB pathologies shape subfield microglia responses in the hippocampus

2022-01-06

Abstract excerpt

Hippocampal alteration is at the centre of memory decline in the most common age-related neurodegenerative diseases: Alzheimer’s disease (AD) and Dementia with Lewy Bodies (DLB). However, the subregional deterioration of the hippocampus differs between both diseases with more severe atrophy in the CA1 subfield of the AD patients. How AD and DLB-typical pathologies compose the various local microenvironment of the...

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Literature Corpus work: 02e39ba9-2040-55c8-9402-6aacebb86a4e
DOI: 10.1101/2022.01.06.475218

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