Article

Cross-ancestry proteome-wide Mendelian randomization prioritizes 12 plasma protein candidates for breast cancer risk

2026-05-04

Abstract excerpt

The plasma proteome provides a molecular bridge between genetic variation and disease risk, yet its contribution to breast cancer susceptibility across ancestries remains unclear. We conducted a proteome-wide Mendelian randomization (MR) study of 2,923 plasma proteins using cis -protein quantitative trait loci from 34,557 European participants in the UK Biobank Pharma Proteomics Project, integrated with genome-wi...

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Literature Corpus work: 02d0bac5-2b28-5a80-9f0a-5a77705e6310
DOI: 10.64898/2026.05.04.26352055

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