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Article

Genome-wide evaluation of the effect of short tandem repeat variation on local DNA methylation.

Genome research - 1 Feb 2023

Martin-Trujillo Alejandro, Garg Paras, Patel Nihir, Jadhav Bharati, Sharp Andrew J

Abstract excerpt

Short tandem repeats (STRs) contribute significantly to genetic diversity in humans, including disease-causing variation. Although the effect of STR variation on gene expression has been extensively assessed, their impact on epigenetics has been poorly studied and limited to specific genomic regions. Here, we investigated the hypothesis that some STRs act as independent regulators of local DNA methylation in the...

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PMID: 36577521
DOI: 10.1101/gr.277057.122
PMCID: PMC10069470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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