Article

Multi-tissue analysis reveals short tandem repeats as ubiquitous regulators of gene expression and complex traits

2018-12-13

Abstract excerpt

Short tandem repeats (STRs) have been implicated in a variety of complex traits in humans. However, genome-wide studies of the effects of STRs on gene expression thus far have had limited power to detect associations and provide insights into putative mechanisms. Here, we leverage whole genome sequencing and expression data for 17 tissues from the Genotype-Tissue Expression Project (GTEx) to identify STRs for whic...

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Literature Corpus work: 61ce58f0-e771-56fb-9663-34360c9d0ec2
DOI: 10.1101/495226

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