Article

Rigidity, normal modes and flexible motion of a SARS-CoV-2 (COVID-19) protease structure

2020-03-12

Abstract excerpt

The rigidity and flexibility of two recently reported crystal structures (PDB entries 6Y2E and 6LU7) of a protease from the SARS-CoV-2 virus, the infectious agent of the COVID-19 respiratory disease, has been investigated using pebble-game rigidity analysis, elastic network model normal mode analysis, and all-atom geometric simulations. This computational investigation of the viral protease follows protocols that...

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Literature Corpus work: 02abfad8-c546-5782-a3bc-b23f523085b6
DOI: 10.1101/2020.03.10.986190

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