Article

Impact of emerging mutations on the dynamic properties the SARS-CoV-2 main protease: an <i>in silico</i> investigation

2020-05-29

Abstract excerpt

The new coronavirus (SARS-CoV-2) is a global threat to world health and its economy. Its main protease (M pro ), which functions as a dimer, cleaves viral precursor proteins in the process of viral maturation. It is a good candidate for drug development owing to its conservation and the absence of a human homolog. An improved understanding of the protein behaviour can accelerate the discovery of effective therapi...

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Literature Corpus work: a7e26cb1-b6d3-585b-b415-c6212ba3c83b
DOI: 10.1101/2020.05.29.123190

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