Article
MDR1 polymorphisms are not related to Xeliri and Xelox chemoresistance in colorectal cancer
2019-09-10
Abstract excerpt
<title>Abstract</title> <p>Background Multidrug resistance member 1 (MDR1) is located on chromosome 7 and encodes P-glycoprotein (Pgp), which is universally accepted as a drug resistance biomarker. MDR1 polymorphisms may change either the protein expression or function, suggesting its possible association with cancers, including colorectal cancer (CRC). Thus, this study aimed to determine the effects of MDR1 poly...
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Identifiers and source
- Literature Corpus work
- 02957bca-ef3e-5210-9def-14953c16226d
- DOI
- 10.21203/rs.2.14185/v1
