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Article

Polymorphisms of GSTP1 is associated with differences of chemotherapy response and toxicity in breast cancer.

Chinese medical journal - 1 Jan 2011

Zhang Bai-Lin, Sun Tong, Zhang Bao-Ning, Zheng Shan, Lü Ning, Xu Bing-He, Wang Xiang, Chen Guo-Ji, Yu Dian-Ke, Lin Dong-Xin

Abstract excerpt

BACKGROUND: Although chemotherapy is one of the most important treatments of breast cancer, it is limited by significant inter-individual variations in response and toxicity. The metabolism of epirubicin (EPI) and cyclophosphamide (CTX) is mainly mediated by cytochrome P450s (CYPs) and glutathion...

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Source

Identifiers

PMID: 21362365

Genes

GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21362365-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Polymorphisms of GSTP1 is associated with differences of chemotherapy response and toxicity in breast cancer.PMID 21362365Read ↗

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