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Article

MDR1 gene polymorphisms: possible association with its expression and clinicopathology characteristics in colorectal cancer patients.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011

Samanian Sara, Mahjoubi Frouzandeh, Mahjoubi Bahar, Mirzaee Rezvan, Azizi Rasool

Abstract excerpt

AIM: Over-expression of some genes, such as MDR1, can increase the level of chemotherapy drug afflux and limit the effectiveness of treatment. We aimed to investigate the effect of MDR1 polymorphisms on its expression level and related characteristics in Iranian colorectal cancer patients. METHODS: Tumor, normal mucosal tissue and blood samples from CRC patients and blood samples from healthy controls (n=60) were...

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PMID: 22394004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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