Article
MDR1 gene polymorphisms and imatinib response in chronic myeloid leukemia: a meta-analysis.
Pharmacogenomics - 1 Apr 2014
Zu Bailing, Li Yajuan, Wang Xin, He Dali, Huang Zhenglan, Feng Wenli
Abstract excerpt
BACKGROUND: MDR1 gene polymorphisms were demonstrated to be associated with interindividual variability of imatinib response for chronic myeloid leukemia (CML) patients in several studies; however, the results have been inconclusive. MATERIALS & METHODS: To clarify the effect of common MDR1 variants on clinical response to imatinib, we performed a meta-analysis to quantify the accumulated information from genetic...
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