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Article

Correlation between MDR1 methylation status in the promoter region and MDR1 genetic polymorphism in 194 healthy Chinese Han subjects.

Pharmacogenomics - 1 Dec 2008

Jiang Zhi-Ping, Xu Ping, Liu Rong-Rong, Li Huan-De, Wang Guan-Ping, Zhao Xie-Lan, Chen Fan-Ping

Abstract excerpt

AIMS: To investigate the correlation between the methylation status in the MDR1 promoter region and the MDR1 genetic polymorphism. METHODS: A total of 194 unrelated subjects (105 men and 89 women) with a median age of 26 years were enrolled in this study. DNA was extracted and PCR-RFLP was performed for C1236T, C3435T and G2677T/A polymorphism genotyping. The combined bisulfite restriction analysis (COBRA) method...

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Identifiers

PMID: 19072639
DOI: 10.2217/14622416.9.12.1801

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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