Article

Delineating mouse β-cell identity during lifetime and in diabetes with a single cell atlas

2022-12-22

Abstract excerpt

Multiple pancreatic islet single-cell RNA sequencing (scRNA-seq) datasets have been generated to study development, homeostasis, and diabetes. However, there is no consensus on cell states and pathways across conditions as well as the value of preclinical mouse models. Since these challenges can only be resolved by jointly analyzing multiple datasets, we present a scRNA-seq cross-condition mouse islet atlas (MIA)....

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Literature Corpus work: 1e46d6da-ea25-546f-ae81-1b603e509475
DOI: 10.1101/2022.12.22.521557

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