Article

Invasive FoxM1 phosphorylated by PLK1 induces the polarization of tumor-associated macrophages to promote immune escape and metastasis, amplified by IFITM1

2023-08-21

Abstract excerpt

<title>Abstract</title> <p>Background Understanding the mechanism behind immune cell plasticity in cancer metastasis is crucial for identifying key regulators. Previously we found that mitotic factors regulate epithelial-mesenchymal transition, but how these factors convert to metastatic players in the tumor microenvironment (TME) is not fully understood. Methods The clinical importance of mitotic factors was a...

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Literature Corpus work: e8ce6667-8a72-54b0-9702-adcae8329193
DOI: 10.21203/rs.3.rs-3261219/v1

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