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Establishment of a reference single-cell RNA sequencing dataset for human pancreatic adenocarcinoma

22 Jun 2022

Abstract excerpt

Single-cell RNA sequencing (scRNAseq) has been used to assess the intra-tumor heterogeneity and microenvironment of pancreatic ductal adenocarcinoma (PDAC). However, previous knowledge is not fully universalized. Here, we built a single cell atlas of PDAC from six datasets containing over 70 samples and >130,000 cells, and demonstrated its application to the reanalysis of the previous bulk transcriptomic cohorts...

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PMID: 35847558
DOI: 10.1016/j.isci.2022.104659

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