Article

Mutational and copy number analysis of numerous sorted circulating and disseminated tumour cells to interrogate subclonal evolution in advanced breast cancer.

2023-05-04

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>. Liquid biopsies have been studied as an accessible method to capture spatial tumour heterogeneity and repeatedly evaluate targetable aberrations in cancer. Here, we analysed pure single and pools of circulating and disseminated tumour cells (CTC and DTC) to study genetic heterogeneity. <bold>Methods</bold>. From, three patients with metastatic breast cancer, CTC...

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Literature Corpus work: 02116fb9-00aa-524c-9dd7-83a5b856a832
DOI: 10.21203/rs.3.rs-2824422/v1

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