Article
Treatment response and tumor evolution: lessons from an extended series of multianalyte liquid biopsies in a metastatic breast cancer patient.
Cold Spring Harbor molecular case studies - 1 Dec 2020
Welter Lisa, Xu Liya, McKinley Dillon, Dago Angel E, Prabakar Rishvanth K, Restrepo-Vassalli Sara, Xu Kevin, Rodriguez-Lee Mariam, Kolatkar Anand, Nevarez Rafael, Ruiz Carmen, Nieva Jorge, Kuhn Peter, Hicks James
Abstract excerpt
Currently, clinical characterization of metastatic breast cancer is based on tissue samples taken at time of diagnosis. However, tissue biopsies are invasive and tumors are continuously evolving, which indicates the need for minimally invasive longitudinal assessment of the tumor. Blood-based liquid biopsies provide minimal invasive means for serial sampling over the course of treatment and the opportunity to...
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