Article

A Novel Role for the Tumor Suppressor Gene ITF2 in Lung Tumorigenesis and Chemotherapy Response

2020-02-28

Abstract excerpt

Despite often leading to platinum resistance, platinum-based chemotherapy continues to be the standard treatment for many epithelial tumors. In this study we analyze and validated the cytogenetic alterations that arise after treatment in four lung and ovarian paired cisplatin-sensitive/resistant cell lines by 1-million array-CGH and qRT-PCR methodologies. RNA-sequencing, functional transfection assays and gene-pat...

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Literature Corpus work: 02110002-27f7-51e9-b3c7-d60299f616e9
DOI: 10.20944/preprints202002.0423.v1

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