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Article

MEOX2 mediates cisplatin resistance in ovarian cancer via E2F target and DNA repair pathways

21 Mar 2025

Abstract excerpt

Ovarian cancer (OV) is a leading cause of cancer-related mortality among women worldwide. Despite the success of platinum-based chemotherapy in treating OV, the emergence of cisplatin resistance has significantly compromised its therapeutic efficacy. Therefore, understanding the mechanisms underlying cisplatin resistance and its molecular regulation is crucial for improving patient outcomes. This study, MEOX2 was...

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PMID: 40119426
DOI: 10.1186/s13048-025-01641-2

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