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The Role of Hemoglobin Subunit Delta in the Immunopathy of Multiple Sclerosis: Mitochondria Matters

24 Aug 2021

Abstract excerpt

Background Although the exact pathophysiology of MS has not been identified, mitochondrial stress can be one of the culprits in MS development. Herein, we have applied microarray analysis, single-cell sequencing analysis, and ex vivo study to elucidate the role of mitochondrial stress in PBMCs of MS patients. Methods For this purpose, we analyzed the GSE21942 and GSE138266 datasets to identify the DEGs and hub...

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PMID: 34504491
DOI: 10.3389/fimmu.2021.709173

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