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Article

Spatial proteomic characterization of HER2-positive breast tumors through neoadjuvant therapy predicts response

2020-09-25

Abstract excerpt

Addition of HER2-targeted agents to neoadjuvant chemotherapy has dramatically improved pathological complete response (pCR) rates in early-stage HER2-positive breast cancer. Still, up to 50% of patients have residual disease following treatment, while others are likely overtreated. Here, we performed multiplex spatial proteomic characterization of 122 samples from 57 HER2-positive breast tumors from the neoadjuvan...

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Identifiers and source

Literature Corpus work
019aaf3d-9830-5af5-b18a-b02a75acb040
DOI
10.1101/2020.09.23.20199091
Open publication

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Spatial proteomic characterization of HER2-positive breast tumors through neoadjuvant therapy predicts responseDOI 10.1101/2020.09.23.20199091
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