Article

Spatially informed comprehensive tumor transcriptomic profiling stratifies clinical outcomes in early triple negative breast cancer

2026-07-09

Abstract excerpt

The intensification of neoadjuvant therapy for early triple-negative breast cancer (eTNBC) – through the addition of carboplatin to standard chemotherapy and the incorporation of pembrolizumab – has markedly improved prognosis in recent years. However, this escalation carries a substantial risk of toxicity, and not all patients require the full regimen to achieve benefit. Realizing individualized treatment strateg...

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Literature Corpus work: fef835cc-701f-569d-af1d-56b6d970e35a
DOI: 10.64898/2026.07.06.26357224

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