Article

The neuroprotective effects of α7 nicotinic acetylcholine receptor against mutant copper-zinc superoxide dismutase 1-mediated toxicity

2020-07-14

Abstract excerpt

<h4>Background: </h4> Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the selective and progressive loss of motor neurons. Although many drugs have entered clinical trials, few have shown effectiveness in the treatment of ALS. Previous studies searching for causal genes associated with familial ALS identified the copper-zinc superoxide dismutase 1 (SOD1). Other studies hav...

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Literature Corpus work: 0198496d-c196-51e1-8fa7-32cbd5363e28
DOI: 10.21203/rs.3.rs-38218/v1

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