Article
Diagnosis, pathogenesis and therapeutic targets in amyotrophic lateral sclerosis.
CNS & neurological disorders drug targets - 1 Dec 2010
Costa Júlia, Gomes Catarina, de Carvalho Mamede
Abstract excerpt
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease of the motor system. The diagnosis is clinical, but additional investigations such as electromyography, transcranial magnetic stimulation and neuroimaging have demonstrated their usefulness in supporting diagnosis. Exhaustive research for the identification of molecular markers in the cerebrospinal fluid and plasma of ALS patients have been...
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