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A Genotype-Guided P2Y12-Inhibitor De-Escalation Strategy in Acute Coronary Syndrome: Observational Evidence from the POPULAR-GUIDE PCI

2025-08-28

Abstract excerpt

<h4>Background and Aims</h4> A genotype-guided de-escalation strategy - switching from a potent P2Y12-inhibitor to clopidogrel - may represent an effective and safe approach to reducing bleeding risk in patients with acute coronary syndrome (ACS). This analysis aimed to evaluate the safety and effectiveness of routine genetic testing to guide antiplatelet therapy in clinical practice. <h4>Methods</h4> In this in...

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Literature Corpus work
01182fbf-ae90-5dac-b89b-5a616a7d10c7
DOI
10.1101/2025.08.19.25334023
Open publication

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A Genotype-Guided P2Y12-Inhibitor De-Escalation Strategy in Acute Coronary Syndrome: Observational Evidence from the POPULAR-GUIDE PCIDOI 10.1101/2025.08.19.25334023
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