Article
Genotype-Phenotype Association and Impact on Outcomes following Guided De-Escalation of Anti-Platelet Treatment in Acute Coronary Syndrome Patients: The TROPICAL-ACS Genotyping Substudy.
Thrombosis and haemostasis - 1 Sept 2018
Gross Lisa, Trenk Dietmar, Jacobshagen Claudius, Krieg Anne, Gawaz Meinrad, Massberg Steffen, Baylacher Monika, Aradi Daniel, Stimpfle Fabian, Hromek Julia, Vogelgesang Anja, Hadamitzky Martin, Sibbing Dirk, Geisler Tobias
Abstract excerpt
BACKGROUND: Phenotype-guided de-escalation (PGDE) of P2Y12-inhibitor treatment with an early switch from prasugrel to clopidogrel was identified as an effective alternative treatment strategy in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI). The Testing Responsiveness to Platelet Inhibition on Chronic Antiplatelet Treatment for Acute Coronary Syndromes (TROPICAL-ACS)...
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