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Article

Genotyping-guided approach versus the conventional approach in selection of oral P2Y12 receptor blockers in Chinese patients suffering from acute coronary syndrome.

The Journal of international medical research - 1 Feb 2017

Tam Chor Cheung, Kwok Janette, Wong Anthony, Yung Arthur, Shea Catherine, Kong Shun Ling, Tang Wing Hong, Siu David, Chan Raymond, Lee Stephen

Abstract excerpt

Objective The CYP2C19 loss-of-function (LoF) allele is present in half of the East Asian population and is associated with high on-treatment platelet reactivity (HTPR). This study aimed to investigate whether a rapid genotyping-guided approach is feasible and efficacious for selecting P2Y12 receptor blockers in Chinese patients suffering from acute coronary syndrome (ACS). Methods This was a single-centre,...

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Identifiers

PMID: 28222641
DOI: 10.1177/0300060516677190
PMCID: PMC5536604

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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