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Article

Association between ABCB1 C3435T polymorphism and antiepileptic drug resistance in epilepsy: An updated meta-analysis based on 62 studies.

International journal of clinical pharmacology and therapeutics - 1 Mar 2022

Chen Yue-Yue, Feng Yu-Yi, Chen Yin-Nan, Cao Yun-Ming, Ai Chun-Zhi, Bi Cai-Li, Liu Yong, Li Wei

Abstract excerpt

OBJECTIVE: Previous clinical studies and meta-analyses have shown controversial results on the association between C3435T polymorphism of the ABCB1 gene and anti-epileptic drug (AED) resistance. Based on the fact that sample size and confounding factors could contribute to the inconsistency, we performed an updated meta-analysis by including the most recent studies, and subgroup analysis was conducted to evaluate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34846299
DOI: 10.5414/CP204045

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