Article
ABCC2 rs2273697 and rs3740066 polymorphisms and resistance to antiepileptic drugs in Asia Pacific epilepsy cohorts.
Pharmacogenomics - 1 Mar 2014
Sha'ari Hidayati Mohd, Haerian Batoul Sadat, Baum Larry, Saruwatari Junji, Tan Hui Jan, Rafia Mohd Hanip, Raymond Azman Ali, Kwan Patrick, Ishitsu Takateru, Nakagawa Kazuko, Lim Kheng Seang, Mohamed Zahurin
Abstract excerpt
AIM: To examine the relevance of ABCC2 polymorphisms to drug responsiveness in epilepsy cohorts from the Asia Pacific region. MATERIALS & METHODS: The rs2273697 and rs3740066 polymorphisms were genotyped in 2056 Malaysian (55%), Hong Kong (32%) and Japanese (13%) epilepsy patients. RESULTS: Significant allele association of rs2273697 was observed in Chinese females with epilepsy, Malaysian Chinese patients with...
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