Article

Human HMGN1 and HMGN2 are not required for transcription-coupled DNA repair

2019-11-09

Abstract excerpt

<h4>Summary</h4> Transcription-coupled repair (TCR) removes DNA lesions from the transcribed strand of active genes. Stalling of RNA polymerase II (RNAPII) at DNA lesions initiates TCR through the recruitment of the CSB and CSA proteins. The full repertoire of proteins required for human TCR – particularly in a chromatin context - remains to be determined. Studies in mice have revealed that the nucleosome-binding...

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Literature Corpus work: 009e77fc-c7df-5394-8968-662139700bce
DOI: 10.1101/835868

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