Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inhibition of nucleotide excision repair by high mobility group protein HMGA1.

The Journal of biological chemistry - 16 Sept 2005

Adair Jennifer E, Kwon Youngho, Dement Gregory A, Smerdon Michael J, Reeves Raymond

Abstract excerpt

The mammalian non-histone "high mobility group" A (HMGA) proteins are the primary nuclear proteins that bind to the minor groove of AT-rich DNA. They may, therefore, influence the formation and/or repair of DNA lesions that occur in AT-rich DNA, such as cyclobutane pyrimidine dimers (CPDs) induced by UV radiation. Employing both stably transfected lines of human MCF7 cells containing tetracycline-regulated HMGA1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Pair Mismatch
Share to Circular Dichroism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dose-Response Relationship, Radiation

Share to Interleukin-2 Receptor alpha Subunit

Share to Oligonucleotides

Share to Pyrimidine Dimers

Share to Receptors, Interleukin

Share to Xenopus

Source

Identifiers

PMID: 16033759
DOI: 10.1074/jbc.M505600200

Genes

HMGA1
CPD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inhibition of nucleotide excision repair by high mobility group protein HMGA1.PMID 16033759Read ↗

High mobility group protein B1 enhances DNA repair and chromatin modification after DNA damage.Semantic proximity Read ↗

HMGB1: The jack‐of‐all‐trades protein is a master DNA repair mechanicSemantic proximity Read ↗

HMGB1 interacts with XPA to facilitate the processing of DNA interstrand crosslinks in human cells.Semantic proximity Read ↗

Human HMGN1 and HMGN2 are not required for transcription-coupled DNA repairSemantic proximity Read ↗

Mitochondrial Transcription Factor A Binds to and Promotes Mutagenic Transcriptional Bypass of O4-Alkylthymidine Lesions.Semantic proximity Read ↗

HMGA proteins: isolation, biochemical modifications, and nucleosome interactions.Semantic proximity Read ↗

O-GlcNAcylation of High Mobility Group Box 1 (HMGB1) Alters Its DNA Binding and DNA Damage Processing Activities.Semantic proximity Read ↗

High Mobility Group Box 1 in Human CancerSemantic proximity Read ↗

Repair shielding of platinum-DNA lesions in testicular germ cell tumors by high-mobility group box protein 4 imparts cisplatin hypersensitivitySemantic proximity Read ↗

Construction and analysis of cells lacking the HMGA gene family.Semantic proximity Read ↗

The chromatin structuring protein HMGA2 influences human subtelomere stability and cancer chemosensitivitySemantic proximity Read ↗

Human Papilloma Virus-Dependent HMGA1 Expression Is a Relevant Step in Cervical CarcinogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.